Boost Your Gut Health with GI + Biome Complex™

A resilient gut is foundational to optimal health — influencing digestion, nutrient absorption, immune function, and even mood.*

In this webinar, Dr. Kate Leavens, ND, LAc, explores the science and formulation behind GI + Biome Complex™, a new Enzyme Science innovation designed to support gut barrier integrity, microbiome diversity, and mucosal balance through targeted postbiotic, enzymatic, and botanical ingredients.*

Watch the Webinar Replay

In this session, Dr. Leavens discusses:

• How butyrate and tributyrin support intestinal barrier integrity, microbiome balance, and mucosal healing*

• The function of Lipase Thera-blend® in improving fat digestion and controlled butyrate release across the GI tract*

• The clinical role of Zinc Carnosine (PepZin GI®) in promoting mucosal repair and reducing intestinal permeability*

• The gut health benefits of golden Kiwi Extract ( Livaux®) for supporting regularity, microbiota diversity, and antioxidant defense*

• Practical considerations for practitioners when incorporating GI + Biome Complex into digestive and microbiome-focused protocols*

The Foundation: Butyrate and Tributyrin for Mucosal Energy and Repair

Butyrate is a short-chain fatty acid (SCFA) and key postbiotic metabolite produced by beneficial gut bacteria through the fermentation of dietary fibers. It serves as the primary energy source for colonocytes, the cells lining the intestinal wall, and plays a vital role in maintaining gut barrier integrity and inflammatory balance.*

GI + Biome Complex provides butyrate support through Butyrgen®, a combination of tributyrin (a stable, slow-release butyrate triglyceride) and prebiotic fiber sources.

• Tributyrin provides gradual release of butyrate throughout the GI tract, improving stability and bioavailability.*
• Butyrate supports tight junction integrity, balanced microbiota composition, and mucosal immune regulation.*

A clinical study of 3,000 patients found that 12 weeks of sodium butyrate supplementation significantly improved abdominal discomfort, bowel regularity, flatulence, and quality of life in those with occasional digestive imbalance.*

Lipase Thera-blend®: Broad-Spectrum Enzyme Support

Lipase Thera-blend® ensures complete breakdown of triglycerides and efficient butyrate liberation from tributyrin across the GI tract’s variable pH range.

This technology combines multiple lipase strains with complementary pH activity, ensuring enzymatic support from the stomach through the small intestine.*

By facilitating optimal fat digestion and postbiotic release, Lipase Thera-blend® supports a more balanced gut environment, helping reduce occasional bloating and promoting nutrient assimilation.*

Zinc Carnosine (PepZin GI®): Mucosal Resilience and Barrier Protection

The synergistic combination of zinc and L-carnosine (PepZin GI®) has been clinically shown to support the integrity and repair of gastrointestinal mucosa.*

• Zinc and carnosine adhere to the stomach lining for extended local activity — up to twice as long as individual components alone.*
• This complex has demonstrated the ability to reduce intestinal permeability and support mucosal recovery following physical or metabolic stress.*
• Zinc carnosine’s antioxidant and anti-lipid-peroxidation actions help maintain healthy inflammatory balance and tight junction structure.*

A double-blind study found a 71% improvement in intestinal barrier function following two weeks of zinc carnosine supplementation in physically stressed individuals.*

Golden Kiwi Extract: Natural Support for Regularity and Microbiome Balance

Derived from New Zealand-grown golden kiwi fruit, provides a unique combination of polyphenols, vitamin C, and fermentable fiber that supports bowel regularity, microbial diversity and antioxidant defense.*

Clinical and preclinical studies suggest golden kiwi extract may:

• Promote butyrate-producing bacterial populations*
• Support regular bowel transit time*
• Help reduce oxidative stress and mucosal irritation*

Compared to apple fiber and wheat bran, golden kiwi fiber demonstrates superior fermentability and short-chain fatty acid production, making it a powerful tool for digestive comfort and microbiome modulation.*

Synergistic Benefits of GI + Biome Complex

Together, these key ingredients address the multi-layered needs of the gastrointestinal system:*

 

This formula offers broad-spectrum gut support, making it a valuable clinical option for individuals seeking to maintain healthy digestion, microbial balance, and intestinal comfort.*

Clinical Application and Dosing

• Suggested use: Two capsules daily, or as directed by a healthcare practitioner.*
• Ideal for inclusion in functional GI protocols, especially for patients needing gut barrier and microbiome support.*
• Suitable for co-administration with enzyme, prebiotic, or probiotic regimens.*