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Enzyme therapy - a method of immune therapy for immunologically caused habitual abortions

Dittmar, F.-W.

Gynäkologisch-geburtshilfliche Abteilung (Chefarzt: Prof. Dr. F.-W. Dittmar) des Kreiskrankenhauses Starnberg, Akademisches Lehrkrankenhaus der Ludwig-Maximilians-Universität München

Forum Immunologie 2000, No. 3/2000, II - VIII.

SO 129 (5-02-1)


Background: For patients with immunologically caused habitual abortion so far there are only few therapies possible with limited success and predominantly considerable side effects. 

 Objective: it was the aim of this investigation to rate the benefit of systemic enzyme therapy for pregnant women with habitual abortion in history by means of the course of pregnancy and delivery including fetal outcome. Materials and methods:  144 pregnant women with immunologically caused abortion received a gestagen preparation and an enzyme combination preparation and were observed up to delivery. The current data of pregnancy, birth and child were collected and evaluated.  

 Results:  114 of 144 enzyme treated pregnant women had an inconspicuous course of pregnancy up to the. birth of 114 healthy children. Enzyme therapy caused no unpleasant side effects.  

 Conclusions:  For immunologically caused habitual abortion enzyme therapy is an effective form of immune therapy. The maternal immune system is stabilized by the supplied enzymes whereby the full development of a pregnancy is easier. The further clearing of the molecular mechanisms of action is subject of current research projects. Enzyme therapy can be recommended predominantly for women, who had several abortions receiving the common forms of immune therapy without success and therefore now are looking for a therapeutical alternative. According to the previous experience enzyme therapy is very successful for women with habitual abortion with regard to completed pregnancies, and furthermore well tolerated and also cost-effective.

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