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Influence of Bromelain on Penetration of Antibiotics in Uterus, Salpinx and Ovary

Luerti, M. and Vignali, M. L.

Sacco Hospital, Department of Obstetrics and Gynaecology, University of Milan, Italy.

Drugs Exptl. Clin. Res.1978, 4, 1, pp. 45-48 

322 KA

The determination of levels of amoxycillin and tetracycline in serum, uterus, ovarian tube and ovary in patients treated with these antibiotics and bromelain proved to be higher than in patients treated with the same antibiotics and placebo or indomethacin. It is concluded that bromelain favours the absorption and tissue penetration of antibiotics by mechanisms that are not shared by other antiinflammatory agents.

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