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WAM Essentials, Inc.
Systemic Enzyme Therapy
... Allowing You to Live Your Passion!™ |
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| Evaluation of Serratia peptidase in acute or chronic inflammation
of otorhinolaryngology pathology: a multicentre, double-blind,
randomized trial versus placebo.
Mazzone A, Catalani M, Costanzo M, Drusian A, Mandoli A,
Russo S, Guarini E, Vesperini G.
J Int Med Res. 1990 Sep-Oct;18(5):379-88.
Institute of Clinical Otorhinolaryngology, University of
Naples, Italy. |
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The efficacy and tolerability of Serratia peptidase were
evaluated in a multicentre, double-blind, placebo-controlled
study of 193 subjects suffering from acute or chronic ear,
nose or throat disorders. Treatment lasted 7-8 days, with
the drug or placebo being administered at a rate of two tablets
three times a day. After 3-4 days' treatment, significant
symptom regression was observed in peptidase-treated patients.
There was also a significant reduction in symptoms after
7-8 days for patients in both treatment groups but the response
was more marked in those patients receiving the active drug.
Statistical comparison between the two groups confirmed the
greater efficacy and rapid action of the peptidase against
all the symptoms examined at both stages. Tolerance was found
to be very good and similar for both groups. It is concluded
that Serratia peptidase has anti-inflammatory, anti-oedemic
and fibrinolytic activity and acts rapidly on localized inflammation. |
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