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WAM Essentials, Inc.
Systemic Enzyme Therapy
... Allowing You to Live Your Passion!™ |
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Pharmacoprophylaxis of the arm secondary lymphedema
development after axilla exenteration and radiotherapy
Wald M., Adámek J. and Prausová J.*
Department of Surgery
* Department of Oncology
2nd Medical School, Charles University,
Prague, Czech Republic
XI International Congress of Senology, Cancun -(Mexico), May 13 – 18,
2000, pp. 203-205
495 KA (2-05-1) |
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Summary
Within the chemoprevention at complex therapy of breast carcinoma,
stage I and II, at the Surgical Clinic of 2nd Medical School, Charles
University, Prague (Czech Republic) we administer patients mixture
of proteinases (trypsin, chymotrypsin, papain) supplemented by
thymus extract for 28 days starting on the day 1 after surgery.
Literature data (Rokitansky) show a positive effect of proteinases
on the survival time in patients with breast carcinoma. Furthermore,
we have verified this fact on the animal models. From the literature
it has been known and our 7-year-experience has confirmed the fact
that perisurgical administration of proteinases has a significant
effect on the homolateral arm secondary lymphedema development
after axilla exenteration. While a significance of systemically
acting proteinases on the chemoprevention of breast carcinoma could
not be evaluated so far because of short-term observation (the
longest observation period 2 years), we can confirm that proteinase
pharmacoprophylaxis at complex therapy of breast carcinoma has
reduced lymphedema occurrence in our patients by 50%.
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