| |
WAM Essentials, Inc.
Systemic Enzyme Therapy
... Allowing You to Live Your Passion!™ |
|
|
|
|
|
|
|
|
Proteolytic enzymes: a new treatment strategy
for prosthetic infections?
Selan L, Berlutti F, Passariello C, Comodi-Ballanti MR,
Thaller MC.
Antimicrob Agents Chemother. 1993 Dec;37(12):2618-21.
Istituto di Microbiologia, Facolta di Farmacia, Universita
La Sapienza, Rome, Italy.
|
|
Among the different mechanisms of bacterial
resistance to antimicrobial agents that have been studied,
biofilm formation is one of the most widespread. This mechanism
is frequently the cause of failure in the treatment of prosthetic
device infections, and several attempts have been made to develop
molecules and protocols that are able to inhibit biofilm-embedded
bacteria. We present data suggesting the possibility that proteolytic
enzymes could significantly enhance the activities of antibiotics
against biofilms. Antibiotic susceptibility tests on both planktonic
and sessile cultures, studies on the dynamics of colonization
of 10 biofilm-forming isolates, and then bioluminescence and
scanning electron microscopy under seven different experimental
conditions showed that serratiopeptidase greatly enhances the
activity of ofloxacin on sessile cultures and can inhibit biofilm
formation. |
|
|
|
|
|
Medical Disclaimer: We believe
that the role of nutrition is important to good health, however,
this web site is for informational purposes only and is not
intended to be a substitute for professional medical advice.
Our goal is to provide you, the customer, with the information
necessary for you to make important nutritional and self-help
decisions. We strongly suggest that you share any products
you decide to use with your health care professional for optimal
individual health benefits. Women who are planning on becoming
pregnant or who are pregnant should not take any supplements
without consulting their physician first. Information and statements
on this website regarding dietary supplements have not been
evaluated by the Food and Drug Administration, and are not
intended to diagnose, treat, cure, mitigate or prevent any
disease or health condition.
|
| |
|
© Copyright 2004 WAM Essentials,
Inc. All Rights Reserved.
None of the material contained herein may be reproduced without
the prior written consent of WAM Essentials, Inc. |
|
|
